Microsoft Publisher can be used to create repeating content in a flyer format.
Imagine that you want to subdivide a letter size page – in landscape mode – into three vertical panes, with the same content repeating the the tree panes.
You work with the content in one pane, and when printed, the content will repeat into the other two panes.
The key seems to be to understand the distinctions between page setup and print setup, and when in the Page Setup > Advanced "Custom Page Size Dialog" understanding the distinction between 'Page' and 'Sheet'.
When you click File > Print Preview, you'll see a 3-up presentation with 3 identical content panes.
Here's a rough guide to what worked for me:
File > Page Setup Advanced Custom Page Size Dialog Layout Type: Multiple pages per sheet Page: Page Width: 3.6666" Page Height: 8.5" Options: Target Sheet Size: Custom Sheet width: 11" Sheet height: 8.5" File > Print Setup Printing options: Multiple copies per sheet Paper size: Letter Orientation: Landscape